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While this is generally less than what is observed with GLP-1 agonists like Wegovy, Orlistat can still be an effective tool for individuals, particularly those who struggle with high-fat diets or specific dietary patterns
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7 PIONEER 7 The PIONEER 7 trial, like PIONEER 3, compared oral semaglutide against 100-mg sitagliptin, although this trial differs in that it allowed for flexible dose adjustments of oral semaglutide
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